Working with psychologically rich materials, Rasdjarmrearnsook considers a wide range of subjects that have existed in marginal spaces, including women, the deceased, the insane, and animals. She creates complex narratives that confront societal structures of power and pedagogy. Concerned with systems of language and communication, Rasdjarmrearnsook makes earnest attempts to converse with subjects who don't speak in languages that are comprehended by or even acknowledged by mainstream society.
In 2015, Rasdjarmrearnsook had her first US retrospective at the Sculpture Center, which made several year-end lists, notably in the Guardian and Art in America, and solo shows at Tyler Rollins Fine Arts, New York, and Kyoto Art Center, Kyoto. In 2014, she had solo exhibitions at the Denver Art Museum, Colorado, 4A Centre for Contemporary Asian Art in Sydney, Drill Hall Gallery, Canberra, and the University of Sydney.
For the past 25 years, Rasdjarmrearnsook's videos and installations have been regularly shown throughout the world. She represented Thailand at the Venice Biennale in 2005, and has been featured in many international exhibitions including Documenta, the Sydney Biennale, the Gwangju Biennale, the Istanbul Biennial, the Johannesburg Biennial and the Carnegie International. Rasdjarmrearnsook is also a respected professor in Thailand's leading art program in Chiang Mai University, where she has spearheaded one of the first media and theory departments in the country.